The second virial coefficient as a predictor of protein aggregation propensity: A self-interaction chromatography study
نویسندگان
چکیده
منابع مشابه
Second virial coefficient studies of cosolvent-induced protein self-interaction.
Protein self-interaction is important in protein crystal growth, solubilization, and aggregation, both in vitro and in vivo, as with protein misfolding diseases, such as Alzheimer's. Although second virial coefficient studies can supply invaluable quantitative information, their emergence as a systematic approach to evaluating protein self-interaction has been slowed by the limitations of tradi...
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Applications of the second virial coefficient: protein crystallization and solubility
A number of citations in the article by Wilson & DeLucas [(2014). Acta Cryst. F70, 543-554] are corrected.
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ژورنال
عنوان ژورنال: European Journal of Pharmaceutics and Biopharmaceutics
سال: 2015
ISSN: 0939-6411
DOI: 10.1016/j.ejpb.2015.07.025